5 - dermatology mcqs - 1 to 6

1) Examples of Scarring alopecia are all except

a. Cutaneous lupus

b. Lichen planus

c. Alopecia areata

d. Sarcoidosis

Answer (c ) Alopecia Areata

Reference: Harrison 16^th Edition Page 298

2) Herald patch is commonly seen with

a. Pitryasis rosea

b. Pityriasis Versicolor

c. Erysipela

d. Dermatophytosis

Answer (a) Pityriasis Rosea

Reference: Harrison 16^th Edition Page 292

3) Erythema nodosum leprosum occurs in

a. Lepro matous leprosy

b. Tuberculoid leprosy

c. Both

d. None

Answer (a) Lepramatous Leprosy

Reference: Harrison 16^th Edition Page 969

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4) Wood Lamp not useful in

a. Tinea capitis

b. Warts

c. Tinea versicolor

d. Erythrasma

Answer b) Warts

Reference: SARP - SARP 6th Edition : Page PARAS - PARAS 4th Edition : Page Sure Sucess in PG Entrance 1st Edition :

Conditions	Finding
Flexures	Accentuated
Post inflammatory	Fades
Vitiligo	Totally white
Erythrasmna(C.Minutissimum)	Coral Red
Tinea Capitis	Brilliant Green
Tinea Versicolor	Dull Yellow
Pseudomonas	Pale Blue/Green
Tuberous Sclerosis (Ash Leaf)	Blue white
Urine in Porphyria Cutanea Tarda	Pinkish Red

5) Poikiloderma presents with

a. Atrophy,

b. Telangiectasia,

c. Pigmentary changes

d. All of the above

Answer d: All of the above

Reference: Poikiloderma of Civatte refers to erythema associated with a mottled pigmentation seen on the sides of the neck, most commonly in women. Civatte first described the condition in 1923. Poikiloderma of Civatte is a condition affecting the skin. Many consider it to be a reaction pattern of the skin and not a disease. The term poikiloderma refers to the combination of atrophy, telangiectasia, and pigmentary changes (both hypopigmentation and hyperpigmentation). Poikilodermatous lesions may be seen in certain genodermatoses (Rothmund-Thomson syndrome, Bloom syndrome, dyskeratosis congenita), in connective tissue diseases (dermatomyositis, lupus erythematosus), in parapsoriasis/mycosis fungoides, and in radiodermatitis.

6) PUVA therapy is indicated in

a. Psoriasis

b. Vitiligo

c. Alopecia Areata

d. Any of the above

Answer d) Any of the above

Reference: Harrison 15^th Edition Chapter 57

4 - acne mcqs

Question 1
What is not true with regard to Propionibacterium acnes:
It is an anaerobic, gram-positive bacterium
It uses sebum as a nutrient for growth
Is not a normal inhabitant of the skin------------------
Its number correlates with the concentration of triglycerides in sebum

Question 2
The most pathognomic sign of acne is presence of:
Comedone--------
Pustule
Papule
Cyst

Question 3
Factor that is not responsible for acne flare-up:
Squeezing at blemishes
Oily food------------
Changing hormonal levels in adolescent girls
Hard scrubbing of the skin

Question 4
Which of the following is not responsible for the black colour of the open comedones (blackheads):
Oxidation of melanin
Dirt--------------
Interference in transmission of light through compacted epithelial cells
Presence of certain lipids in sebum

Question 5
According to Global Acne Grading System (GACS), acne is considered moderate if Global score is:
1-18
19-30------------
31-38
>39

Question 6
Unique therapeutic option for female acne sufferers, particularly those seeking contraception is:
Contraceptive containing estrogen-------------
Contraceptive containing only progesterone
Any of the above
None of the above

Question 7
Which of these medications can cause acneiform lesions:
Corticosteroids-------------
Tretinoin
Azelaic acid
Adapalene

Question 8
Clues that help to determine whether acne is due to an excess of androgen hormones are:
Hirsutism
Premenstrual acne flares
Irregular menstrual cycles
All the above--------------

Question 9
What is the minimum time for which one should wait before switching to a new therapy for acne:
2-3 weeks
6-8 weeks--------------
4 –5 months
10-12 months

Question 10
To avoid complications which test should be done in a married female before starting Isotretinoin treatment for acne:
Liver function test
Pregnancy test-------------
Glucose tolerance test
Renal clearance test

Question 11
Sudden and profuse lesions erupting after the age of thirty call for investigations of which of the following:
Pituitary
Adrenal cortex
Gonads
All the above-------------

Question 12
Which of these drug suppresses all the four aetiological factors responsible for acne:
Isotretinoin-------------
Tretinoin
Clindamycin
Benzoyl peroxide

Question 13
Tretinoin is used as a topical agent for treatment of acne because of it’s:
Comedolytic effect------------
Keratolytic effect
Bactericidal effect
All of the above

Question 14
Which of these is used as an oral medicine for acne:
Azelaic acid
Tretinoin
Adapalene
Isotretinoin-------------

Question 15
Bleaching of hair is a side effect associated with which of the following medications for acne:
Sulfur
Benzoyl peroxide------------
Retinoids
Isotretinoin

3 - atopic dermatitis

3 - an extra fold of skin beneath the lower eyelid seen in ATOPIC DERMATITIS is called ?

a- dennie's line
b- pinni's line
c- chinni's line
d- nanni's line

answer is a - dennie's line . also called as dennie's infraorbital fold . atopic dermatitis is the cutaneous expression of the atopic state , characterised by a family history of asthma , hay fever , or dermatitis in upto 70 % of patients . also called as atopic eczema . eczema is synonymous with dermatitis . THE PICTURE BELOW SHOWS THE DENNIE'S LINE IN A PATIENT WITH ATOPY .

2 - freckle OR ephelid

2 - a flat coloured lesion ( color different from the surrounding skin ) , less than 2 cm in diameter , not raised above the surface of the surrounding skin is called ?

a- macule
b- patch
c- papule
d- nodule

the answer is a- MACULE . a " freckle " or ephelid , is a prototype pigmented macule . other examples of macules are vitiligo and tinea versicolor about which we will know later.

the patch differs from the macule only in size , a patch is a large flat colored lesion ( color different from the surrounding skin ) which is greater than 2 cm in diameter .


the pictures above clearly show u wat freckles are . picture 1 shows Freckled twins. predisposition to freckles is genetic and is related to the presence of the MC1R gene variant.

Freckles are small colored spots of melanin on the exposed skin or membrane of people with complexions fair enough for them to be visible.

Having freckles is genetic and is related to the presence of the melanocortin-1 receptor MC1R gene variant, which is dominant. Freckling can also be triggered by long exposure to sunlight, such as suntanning. When the sun’s rays penetrate the skin, they activate melanocytes which can cause freckles to become darker and more numerous, although the distribution of melanin is not the same. Fair hair such as blonde, or more commonly red hair, are usually common with the genetic factor of freckles, but none so much as fair or pale skin.

Freckles are predominantly found on the face, although they may appear on any skin exposed to the sun. Freckles are rare on infants, and more common on children before puberty; they are less common on adults.

Children who do not produce enough melanin to protect their skin against harmful rays from the sun develop temporary freckles associated with childhood that usually go away upon puberty, once more melanin is produced. People with the fairest skin often do not produce enough melanin, and so freckles are present after puberty and into adulthood, indicating that individual as a genetic carrier for freckles.

Upon exposure to the sun, freckles will reappear if they have been altered with creams or lasers and not protected from the sun, but do however fade with age in some cases. Freckles are not a skin disorder. People with a predisposition to freckles may be especially susceptible to sunburn and skin cancer, and should therefore take extra care to protect themselves in the sun with a daily sunblock of at least SPF 15.
Freckled twins. Predisposition to freckles is genetic and is related to the presence of the MC1R gene variant.
Freckled twins. Predisposition to freckles is genetic and is related to the presence of the MC1R gene variant.

SO WANNA KNOW WAT EPHELIDS ARE ?

Two types of freckles

Ephelides is a genetic trait. It’s used to describe a freckle that is flat, light brown or red, and fades in the winter. Ephelides are more common in those with light complexions and with the regular use of sunblock, can be suppressed.

Liver spots (also known as sun spots) are freckles that do not fade in the winter. Rather, they form after years of exposure to the sun. Lentigines are more common in older people.

1- largest organ in human body

1- which of the following is the largest organ in the human body?

a- liver
b- skin
c- spleen
d- brain

---- answer is b .obviously the answer has to be skin , otherwise y wud i post this question under dermatology . the skin forms approximately 8% of the total body mass . the surface area of the skin in a man weighing 90 kg and with a height of 1.8 m is 2.2 square meters . when we talk about the thickness of the skin it varies depending on the maturation , ageing and regional specifications but generally an average of 1.5 to 4 mm is accepted . gotta accept the values as they are given in GRAY'S ANATOMY 39 TH EDITION - PAGE 157 .