7q. which is the layer of skin that contains dendritic cells of immune response ?
- stratum basale
- stratum spinosum
- stratum granulosum
- dermis
answer : both a and b are answers. Mostly stratum spinosum . refer grays anatomy thirty-ninth edition page 162 .
--- to answer this question you need to know first
Q: what is a dendritic cell ?
Answer: any cell in the body which has radial projections from its cell body ( like sun and its rays ) is called dendritic cell. A typical example for this type of cell is neuron cell body.
--- next you will have to know
Q: what are the dendritic cells present in the skin ?
Answer : there are 2 types of dendritic cells in the skin , they are MELANOCYTES which are the melanin producing cells and the LANGERHANS CELLS.
--- then you must be wondering
Q: what are the dendritic cells of the skin that are involved in immune response ?
Answer : the langerhans cells are the first defense against any antigen entering the skin . they function as antigen presenting cells .
--- a doubt again
Q: what is an antigen presenting cell ?
Answer : it catches hold of the antigen ( in lay man terms ) and gives it to the
T-lymphocytes which does the remaining work . so as langerhans cells are antigen presenting cells , they are involved in the immune response .
--- so now we know that langerhans cells are the dendritic cells of the skin that are involved in the immune response. Now to answer this question you will have to know
Q: In which layers of the skin are these langerhans cells present ?
Answer : these langerhans cells are present in the epidermis of the skin .
--- so you have excluded option d which is dermis . but to answer this question you will have to know
Q: in exactly which layers of the epidermis are these langerhans cells present ?
Answer : the langerhans cells are present in stratum spinosum and stratum basale . ( page 162 – 39 th edition – grays anatomy ).
--- The wikipedia article on langerhans cell says they are mostly seen in stratum spinosum . so if you are asked a question
Q: in which layer of epidermis are the langerhans cells mostly seen ?
Answer : stratum spinosum .
--- if the question requires one answer then it will be stratum spinosum , but if u are attempting a question which has multiple answers like PGI CHANDIGARH PAPER , then u will have to mark stratum basale too .
--- there will be many enthusiastic people who wanna know
Q: what are all the layers of epidermis ?
Answer : epidermis is made up of 5 layers . from above below they are :
- stratum corneum ( also called cornified layer )
- stratum lucidum ( also called clear layer )
- stratum granulosum ( also called granular layer )
- stratum spinosum ( prickle cell layer )
- stratum basale ( basal layer )
( CLG SB – Clinical Lecture Gallery Special Biriyani – funny mnemonic from my college days )
--- there will be over enthusiastic people like me who wanna know
Q: what are the layers of dermis ?
Answer : 1. papillary layer ( just below epidermis followed by )
2. reticular layer and ( finally )
3. hypodermis .
--- lets stop it here for this question are we are gonna go on for ever .
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